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Friday, April 27, 2012

HISTORY OF DISCOVERY OF VITAMIN K

In 1929, Danish scientist Henrik Dam (Henrik Dam) describe beriberi in chickens that were on the synthetic diet. The main feature of it was haemorrhage - bleeding in the subcutaneous tissue, muscle and other tissues. Add yeast as a source of vitamins B, and fish oil, rich in vitamin A and vitamin D, does not eliminate the pathological phenomena. It turned out that the healing effect with grain cereals and other plant products. Substances which cure hemorrhages, were named vitamin K, vitamin or coagulation, because it was found that bleeding in the experimental birds, for example, associated with decreased ability of blood to clot.

Edward Doyzi in 1936, tried to identify with stops plant opened in 1929, Danish biochemist Henrik Dame vitamin called it vitamin K (from the English «koagulations» - clotting). None of yarrow or with plantain then select the vitamin failed. As it turned out later, there was a small amount.
 In 1939, the laboratory Carrera was first isolated from alfalfa vitamin K, was named filohinon. That same year, Binkley and Doyzi received from rotting fish meal with substance antyhemorahichnoyu action, but with other properties, the preparation isolated from alfalfa. This factor received the name of vitamin K 2 in contrast to the vitamin from alfalfa, called vitamin K 1.On top Doyzi synthesized artificial vitamin K 3 - medion. 

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