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Friday, June 1, 2012

Vitamin A to fight against Leukemia

 More simple enough vitamins and organic substances which are not used as a source of energy but are essential for life. In terms of their chemical composition, are completely different from each other. Are classified into two main groups, fat-soluble and hydrosoluble. A is a fat-soluble vitamins, which is soluble in lipids, D, E and K, along with vitamins. The food is fat and body fat accumulation can not be taken every day. Vitamin A in our body, also known as erretinol, may be obtained in two different ways. On the one hand, can be manufactured from carotenes, vitamin A, these are pioneers. Carrots, pumpkin, spinach, cabbage and potatoes are the vegetables. On the other hand, can be absorbed organismoetatik are fed vegetables, milk, butter, cheese, egg yolk, liver and fish liver oils.


Our body is not affected by transformation of vitamin A does not affect fisiologikorik change. Therefore, it is necessary to obtain the derivatives, ie, erretinoideak. This change occurs in the liver and deposited in the cells after they have become erretinoide. There are three main functions of our body Erretinoideei: cell death and proliferation desberdintzapena. Ten years ago the Department of Cell Biology and Histology University erretinoideek how to strengthen the study of cell death began. This ability to cause cell death that was certain to die, such as cancer cells. Some cells lost the ability to divide and are aging, and eventually to death. There are two types of death: necrosis and apoptosis. Necrosis, the cell is subjected to a very large and unexpected losses in the dismantling of the cell. This is usually a physical problem or lack of oxygen occurs, and eventually loses control of the cell membranes of the analysis, the cell contents scattered.


Apoptosis, the cell has a capacity. It is necessary to control cell death and the program. Our body is a mechanism essential to continue to function properly. If you do not kill cells with defects in apoptosis can lead to serious problems in the functioning of the body. All cells have the ability to perform apoptosis, but is not required in all cells. Is necessary only, and is activated in response to this external and internal stimuli. Erretinoideak for substances such as the modulator. Researchers at the University of Erretinoide erretenamida was chosen for the study. This is a synthetic, so it is not a substance synthesized in our bodies. Are used to treat some other natural Erretinoide disease, such as skin, but high doses are required, and the body becomes toxic is not well supported. Hence the synthetic erretinoide.


Linfoblastikoan erretinamidak have studied the influence of the University of  Leukemia, and this is linfiblastoen cancer. Those who have lost control of the cell cycle, divided by a constant, accumulation in bone marrow and blood cell production difficult. 95% of affected people die due to the influence of Erretinamidaren linfoblasto have seen that. This is because the increase in oxidative stress within cells, which activates the mechanisms of programmed cell death. As a result, the damaged cells die and damage the cells have almost no sense. Have shown that cells exposed to linfiblastikoa erretinamidak only kills leukemia cells and not healthy. Why do not affect healthy cells that researchers continue to investigate and found that several factors. Erretinamidan-based medicines, before these factors must be carefully considered and tailored treatments for each patient.

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